HIV – the virus that is the premier religious symbol of being gay – is now said to be preventable from becoming infectious.**
When you read the gobbledygook these sci-fientists write about this stuff it’s like taking a trip with Dr. Spock through space, except he actually uses logic, these guys don’t.
The fantastical journey through HIV/SPACE is wrought with scientific mumbo jumbo, used to confuse.
Then of course, since this is coming from “experts” in the field, when it’s presented, what lay person can grasp anything other than the statement of HOPE that like OMG/HIV infection could be stopped! Hail science!
**The article is archived here at Archive.org and for convenient and important study it is also archived here with highlighted areas of primary concern:
A new study had found a way to prevent HIV (Human Immunodeficiency Virus) from developing into an infectious agent. The virus, responsible for AIDS (Acquired Immune Deficiency Syndrome) caused the death of more than 35 million people across the globe so far and continues to run largely unabated once it infects someone.
This new study brings hope that the scenario might end for good. It was led by researchers of both the University of Pittsburgh School of Medicine and the University of Delaware (UD). The findings appeared in Nature Communications on Nov. 24. The interdisciplinary research team conducted seven years of detailed studies on the structure of HIV, both in early and later stages of its life cycle before making their breakthrough.
“People used to be fixated on the static structures of viruses, but they are not rock solid,” said Tatyana Polenova, professor in UD’s Department of Chemistry and Biochemistry.
“Viruses like HIV and their constituent protein and nucleic acid molecules are dynamic entities that are constantly expanding and shrinking, Their motions are like breathing,” she said.
Before looking at the way the team broke the virus’ progress towards an infectious agent, a little background into what happens while the HIV virus develops would be useful. When the virus develops, the protein building blocks in its body get cleaved from the master protein termed Gag. But the final step in the virus’ evolution — from being noninfectious to infectious — had remained a mystery. In the present study, the team sought an answer to this.
With the aid of cutting-edge technology, the team found that a major peptide called spacer peptide 1 (SP1) needed to be very mobile if the final stage was to happen (peptides are short chains of amino acid molecules). Otherwise, the enzyme that acts as a cleaver wouldn’t be effective.
Polenova mentioned this curious phenomenon when she said, “This peptide is always there in the final maturation step, but we were surprised that it is so disordered and dynamic.”
Now that the researchers found that the SP1 peptide getting cut was a key reason why the virus turned infectious, their next search was to prevent that from happening. After numerous experiments, they found Bevirimat, an anti-HIV inhibitor could interact with the SPI peptide and prevent the virus from turning infectious. However, the efforts to create an administrable drug to prevent HIV from turning infectious are still going on.
“We have to have a sense of these short-lived molecular fluctuations and processes — of protein cleavage and capsid generation. To add a new generation of capsid inhibitors to prevent HIV, you have to have very specific times and rates at which these drugs will works,” said Juan Perilla, an assistant professor at UD.
Interestingly, this study also points to a new direction in which plenty of scientific research seems to be moving — from a lone scientist or scientists from the same discipline working hard at the lab to a more inter-disciplinary effort.
Other than the universities already mentioned, teams from the University of Illinois, National Cancer Institute and the Vanderbilt University Medical Centre, collaborated for the study.
Ok, let’s now get out the frog, time to dissect this garbage. I am going to do the stuff that you would want to cover your eyes for –
Ok that’s done, now you can look. Here are some of the key points I want to address:
- structure of viruses are not rock solid
- they are dynamic, always changing
- the master protein called Gag – comon’ this is obvious – inside joke!
- final step from being not infectious to infectious has always been a mystery – if this is so how is it possible that they can create all these drugs that have forever claimed such lofty goals of controlling HIV
- SP1 – Spacer Peptide 1 – Greetings Captain – this journey through spacer we arrive at the peptide galaxy
- peptide getting cut is a major factor of it becoming infectious – ‘scuse me why is it now being said to be “a factor” and not “the factor” – this is the most obvious huckster ploy that used car sales men/women/transexuals use – say one thing then say another – they just contradicted themselves
- protein cleavage and capsid generation – picture protein which is used by cells for repair being broken down into pieces – this is more sales talk, extra words that really don’t mean anything – this is the natural process in the body, protein is cut into pieces by the chef with a protein cleaver – nothing new
- capsid generation – capsid is the protein shell of a virus according to Wikipedia “the capsid contains the genetic material of the virus”
Ok, so the capsid is what they are attacking. Take for example the CMV virus (note I just said virus twice). CMV is the CytoMegaloVirus. It’s Herpes. Who knew. It has a capsid coating like crispy rice cereal can have a sugar coating. To supposedly kill the coating, you kill the way the coating operates. That is basically what they are trying to get whomever they can to believe this garbage to believe. Sugar also has a , that way you are not getting too much sugar in your diet. The coating (capsid) contains the genetic material of the crispy rice is what they want you to believe. This is what they are presenting, unicorns that have a sugar coating.
So if A – structures of viruses are not rock solid and B – the capsid (shell of the virus) is what they are supposedly stopping with an inhibitor, how on God’s rainbow unicorn filled Earth is the inhibitor (drug) going to inhibit moving targets? Likely, as with all AIDS/DRUGS they will drop nuclearinhibitor drugs to bomb the hell out of it all, or better put, they will use drug cleaver inhibitors to stop it from being cut it all into pieces as that is the newly discovered last step in the process of HIV/REPLICATION.
Problem is, inhibitors can’t pick and choose what they inhibit on what. So what you have is another sales pitch. The process of inhibiting via drug modalities cannot pick and choose what proteins it stops getting cleaved. In other words, since your body needs cleavers, that is breaking down proteins, the inhibitors stop protein break down (thus replication of HIV) but it also stops break down of protein needed for cells to rebuild into muscle, organ tissue, blood cells, etc.
To make this more visually understood, picture a fine cleaver manufacturer in Paris, France that produces/replicates the best cutlery on Earth. The liberals in the USA influence their election on Twitter, putting in a president that approves laws to control guns and knives in order to save lives – part of the law states that all cleaver manufacturers need to be buried in cement, thus stopping replication of cleavers, thus putting an end to death.
Feature image shows a real Unicorn that was discovered by scientists while traveling through vast space of the medical community mindiverse and is by Royroydeb (Own work) [CC BY-SA 4.0 (https://creativecommons.org/licenses/by-sa/4.0)], via Wikimedia Commons